BRUKER AvanceCore NMR instrument

The AvanceCore combines Bruker‘s extensive NMR expertise and streamlined production processes in an extremely cost-effective product. It is geared towards customers for whom resource efficiency is paramount.


The AvanceCore is a full-fledged, two-channel 400 MHz NMR spectrometer.

Cost-effective: Additional features can be flexibly enabled and disabled with software subscriptions. You only pay for what you need, when you need it.

Quality & Performance: The AvanceCore offers the quality and high performance Bruker is known for, now at a lower price.

NMR is an extremely powerful analytical method. In combination with the affordability of the AvanceCore, this makes NMR the ideal tool to address a large range of analytical questions, including structure elucidation and verification, molecular interactions, and quantitation. The AvanceCore solution offers NMR at a price similar to a standard liquid chromatography mass spec instrument.


The AvanceCore is highly cost effective and facilitates uncompromized performance in high-resolution NMR. Outstanding dispersion and signal-to-noise ratio enable mixture analysis down to ppm concentrations. The AvanceCore supports state-of-the-art 2D NMR methods to elucidate molecular structure at the atomic level.


NMR offers many advantages over other analytical techniques. The AvanceCore provides better value for money than other methods:

With NMR, what you see is what is present. Chromatographic analysis requires process steps such as liquid injection or sample evaporation. Potential sample degradation or unwanted reactions complicate the assignment of signals. NMR selectively detects nuclei such as 1H, 13C, 19F and 31P which are present in organic molecules. This is not apparent with other analytical techniques. For example, UV detectors for chromatography miss many substances without a chromophore. IR and mass detectors have similar limitations. With NMR, substances can be identified and quantified against any reference standard. Other analytical methods rely on a reference standard of the same material. 1D NMR experiments can be run with standard parameters for most samples. Several compounds are identified and quantified from a single spectrum. HPLC, for instance, can also deliver good separation and signal-to-noise — provided that the method was optimized for the particular application. NMR helps you to save time and money.


In order to keep costs low, Bruker has streamlined the AvanceCore into three pre-configured packages.

Foundation: In the most fundamental version, the AvanceCore provides high-resolution 1H NMR spectroscopy. The bundle includes a 400 MHz NMR magnet, a console and a 5 mm probe.

Select: The AvanceCore Select includes all the hardware and software for 1H and heteronuclear (13C, 31P…) state-of-the-art experiments.

Convenience: The AvanceCore Convenience includes a 24-position sample changer. The IconNMR software enables open access use and automated routine measurements.

Your instrument can grow with your needs: An existing AvanceCore can easily be upgraded from Foundation to Select and from Select to Convenience.

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