A short review to KNOTTIN proteins database

Knottins proteins are a new division of small disulfide-rich proteins characterized by a very special “disulfide through disulfide knot” in a classification of proteins.This knot is achieved when one disulfide bridge crosses the macrocycle formed by the two other disulfides and the interconnecting backbone.The knot structure implies that knottins contain at least 3 disulfide bridges …

Short review to SDAP: Structural Database of Allergenic Proteins

SDAP is an onine Web based service that integrates a database of allergenic proteins with various computational and bioinformatics tools that can assist structural biology studies related to allergens. SDAP is a useful important tool in the investigation of the cross-reactivity between known allergens from different databases, in testing the FAO/WHO allergenicity rules for new …

Short review to OPIG Antibody Suite v2.0

OPIG is one of useful tools available for analyzing Antibody data and documented in research has expanded its range of tools for antibody/BCR analysis. Here is an updated summary of the OPIG antibody databases and immunoinformatics tools for 2021 NB: Several of our databases/tools [SAbDab, Thera-SAbDab, ABodyBuilder, PEARS, FREAD, Sphinx, ANARCI, Antibody iPatch, EpiPred, SCALOP, …

What is Immunoinformatics ?

Today, New integrated scientific fields, change our vision to future and mechanism of life, And immunoinformatics as a new field of science. Big data relevant to immunology researches has been accumulated due to sequencing of genomes of the human and other model organisms for understanding mechanism of life and protecting life from threats.. At the …

Coronavirus Antibody Database: Increasingly growth report

In May 2020, Group of students from Oxford university released the Coronavirus Antibody Database (‘CoV-AbDab’) to Manage and capture molecular information on existing coronavirus-binding antibodies, and to track what we anticipated would be a boon of data on antibodies able to bind SARS-CoV-2. At the time, They had found around 300 relevant antibody sequences and …

Epitope 3D: Epitope prediction tool

This software Presented by “Bruna Moreira da Silva”, Epitope3D is an epitope prediction tool using graph-based signatures, developed at the “University of Melbourne“, which is an example of a structure-based approach to epitope prediction. It was developed and trained using a curated, non-redundant set of 200 antigen structures with marked epitopes. Individual residues, labeled according …

SeRenDIP-CE : Epitope Prediction Tool

New immunoinformatics tools On the sequence-side by Dr Anton Feenstra presented that is a new solution called SeRenDIP-CE, a random forest method for predicting epitopes from sequence This method is based on deriving a range of features from the antigen amino-acid sequence (172 features across a sliding window of 9 amino acids, incorporating MSA-derived information) …

Why is Immunoinformatics important? Short fast 1 minute answer!

Immunoinformatics is a field of Bioinformatics science concentrating on the molecules in the immunology system. Currently, immunoinformatics has paved the way for a better understanding of some infectious disease pathogenesis, diagnosis, immune system response and computational vaccinology

Do antibodies have epitopes? Immunoinformatics definition: Short fast 1 minute answer!

Immunoinformatics as a new integrated field of science concentrate on the finding epitope, antigens and pathogenesis mechanism. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. The epitope is the specific piece of the antigen to …

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