#Vaccine, #drugs, #DNA & #proteins are 4 main subject of #biology that change face of our world today and usually students asks for how to learn about vaccine better than anyone else? Understanding vaccine mechanism and function need an integrated vision to #immunology, biophysics, protein conformation, biochemistry of #nucleic_acid and #Amino_acids, #bioinformatics and #immunoinformatics, understanding mechanism of #pathogenesis. Understanding #virus or #Bacteria #genetic content and intermediate molecule that regulate pathways through the #cells. After all of this you need science of #protein_engineering and #metabolic_engineering to have a fully vision of #insilico vaccine design and after that you will face, experimental data and #DOE issues (Design of Experiments) to check clinical data for reporting to regulator based on #GLP and other #pharmacopeia rules and laws. After all of that, remember, science always have one amazing thing to surprise you.
Now Lets take a look at these concepts differently.
Today we are living in #Vaccine_century and new technologies helped us to produce #vaccine_for_kids and pass big #pandemic like #Covid19. New #RNA & #DNA #vaccines_work accurately and make #immunity in human #blood. But by #mutation in previous #Virus & #Bacteria, we need #Vaccine_Update to get #immune from #pathogen such as what we see in #Pfizer that update its #mRNA_Vaccine made by #BioNTech against variety of #Omicron from #CoronaVirus19 that approved by #FDA. And today we see social opposition movement and #new_music made for this such as #Vaccine_nocap published and make a resistance against #vaccine_passport. Previous vaccine technology was based on #Antigen #protein #molecule and #epitope_mapping but today based on #bioinformatics science that integrate different field of #biology such as #biophysics, #biochemistry, #genomics, #proteomics and #metobolomics that used #synthetic_biology, new #vaccine_technology developed that make a billion #dollar #money earning #biopharmaceutical and #pharmaceuticals companies like #JNJ, #Roche, #Pfizer, #Eli_Lilly, #Novo_Nordisk, #Regeneron and #Alexion_pharmaceuticals that are under control of FDA: #America Food and #drug administration that act as a regulator for new #recombinant_proteins, and #biotechnology products to become as a drug in #drugstore. These companies are working on next generation of #personal_medicine to cure diseases from #STDs like #HIV, #HPV, #Chlamydia and #Syphilis to very special cure method that make top expensive drugs such as #Zolgensma, #Glybera, #Luxturna, #Ravicti, #Carbaglu, #Soliris and #Brineura that change our world today. All of these are available for our researchers based on #molecular #modeling and #simulating software such as #Chemkin, #CP2K and #Desmond, and soon in the world of #genetic_engineering and #protein_engineering, new software developed based on #molecular_docking in #atomic and #quantum size modeling such as #AADS, #ADAM & #AutoDock that helps developing new molecules against #diseases with #drug_delivery technologies based on #nanotechnology science. These researches made a big #data that today #health_informatics and #data_mining servers act as a #miners to develop and extract new molecule with optimized function and structure based on #blockchain technology and new #algorithms. These #drug_information made a billion category #database that help #R&D centers to find suitable molecule for special purpose. These scientific movement found that #DNA or #RNA can act as a drug to command live cell for a special purpose in medicine and developing #diagnostic_kits for detecting special molecule or chemical agent in air, water and environment based on #Aptamer Nano #biosensor technologies & #PCR. These kits use unique #conformation or #affinity of a target molecule to #DNA or #mRNA and then activate series of chemical reaction that we detect them with biosensors or chemical sensors. Soon #DNA studies shows unique genetic content can give one person special power to understand or do things easily. This lead to new DNA based pharmaceutical products such as #CRISPER that do live genetic engineering for anti_aging or curing a genetic diseases in someone who is borned with that and today new technologies target to develop #DNA_Vaccine or #RNA_vaccine against diseases such as #Hepatitis, #Diphtheria, #HIB, #Measles and #Meningococcal to create a social immunity against them that medical organization such as #WHO & #HHS (#America_department_of_Health_and_Human_Service) are working on it.
Protein technology also have its own way and engineered #protein_synthesis for making safe and healthy #protein_structure as a #protein_powder, #protein_foods & #pharmaceutical_protein that act as a #hormone such as #insulin, #interferon, #growth_factor, #antibody, #blood_factors, #Enzyme and #Interleukins. And this way is continued.