Bioinformatics is a pioneer field of science that changes every aspect of life science and makes a new vision for humans using different databases and platforms and the primary first database in biology and bioinformatics make a big change in our pathway through the future.

Dayhoff gathered all the available sequence data to create the first bioinformatic database. The Protein Data Bank followed in 1972 with a collection of ten X-ray crystallographic protein structures, and the SWISSPROT protein sequence database began in 1987.